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Duke Economics Working Paper #95-39

Price and Profit Control, New Competitive Dynamics and the Economics of Innovation in the Pharmaceutical Industry


Henry G. Grabowski

Abstract

The focus of this paper is the economics of the pharmaceutical R&D process. Major developments currently impacting the industry include the fact that R&D costs for new drugs are rising very rapidly. Product life cycles are also shortening, meaning there is less time to recover R&D costs and other investment expenditures. Firms are increasingly dependent on a small number of "blockbuster" products to finance future research and development.

This paper provides an overview of several factors influencing the environment for pharmaceutical R&D: trends in costs and product life cycles, returns from new drug introductions, and the consequences of price and profit controls on incentives.

JEL: O34

Published in Symposium on Industrial Policy and the Pharmaceutical Industry, Adrian Towse, ed. London: Office of Health Economics, 1995, pp. 77-91.